SHANDONG SCIENCE ›› 2016, Vol. 29 ›› Issue (2): 25-29.doi: 10.3976/j.issn.1002-4026.2016.02.006

• Pharmacology and Toxicology • Previous Articles     Next Articles

Experiments of antitumor effect of Cordyceps militaris capsules on S180 mouselet

DONG Qi1,GAO Zhi hui2*   

  1. 1.Jinan Laolaishou Biology Group Co. Ltd., Jinan 250014, China;
    2.Shandong University of Traditional Chinese Medicine, Jinan 250355, China
  • Received:2015-12-23 Online:2016-04-20 Published:2016-04-20

Abstract:

We employ S180 solid tumor model at the armpit of mouselet to comprehensively evaluate antitumor effect of Cordyceps militaris capsules on S180 mouselet through the test for such parameters as tumor inhibition rate, immune organ weight and serum NSE, CEA and CA72-4. Results show that medium and high dosage Cordyceps military capsule can significantly inhibit the growth of S180 solid tumor (P<0.05). High, medium and low dosage Cordyceps military capsule can all extend survival time of S180 ascites sarcoma mouselet. High, medium and low dosage Cordyceps military capsule can all reduce the value of serum neuron specific enolase (NSE). Medium and low dosage Cordyceps military capsule can increase the value of serum CEA. High dosage Cordyceps military capsule can increase the value of serum CA72-4, but medium and low dosage Cordyceps military capsule can reduce the value of serum CA72-4. These experiments show that Cordyceps militaris capsule has certain antitumor effect on S180 mouselet.

CLC Number: 

  • R965.1