Abstract:

        We employed the orthogonal experimental approach and took the content of total sugar, reducing sugar and the yield of extraction as measurement indices to select the optimum extraction process of Haisongxin granules. We selected the optimum ingredient ratio of their excipients according to hygroscopicity, granulation and dissolubility. The acquired optimal extraction process of Haisongxin granules is adding eight times the amount of water and extracting threetimes, 1.5 hours each time. The optimum formula is one portion of extract powder and two portions of excipients whose ingredient ratio is 50% sucrose and 50% dextrin. Experimental results show that this process is scientific, reasonable and feasible.

Key words: Haisongxin granule, orthogonal experiment, extraction process, formulation process