SHANDONG SCIENCE ›› 2018, Vol. 31 ›› Issue (1): 23-29.doi: 10.3976/j.issn.1002-4026.2018.01.004

• Traditional Chinese medicine and natural active products • Previous Articles     Next Articles

Optimization of water extraction process for Tonglishu Granule by orthogonal experiment

YANG Long-fei1,DING Xiao-yan2,GAO Yan2,GUO Jin1,SUN Qi-hui1,ZHAO Bo-nian2   

  1. 1.Shandong University of Traditional Chinese Medicine, Jinan 250355,China;2.Shandong Provincial key laboratory of Chinese Medicine Quality Standard Research,Shandong Academy of Chinese Medicine, Jinan 250014,China
  • Received:2017-10-11 Online:2018-02-20 Published:2018-02-20

Abstract:

Based on the orthogonal design, parameters of the water extraction process of Tonglishu Granule were optimized by using gardenin content, peoniflorin content and the extract yield as the index. The experimental results showed that the optimal conditions for water extraction were as follows: eight times of water, extracting two hours and three times. The optimal extraction technology was reasonable and feasible, and the extraction efficiency was high, which could be used as the water extraction technology for Tonglishu Granule, and suitable for industrial producion.

Key words: Tonglishu Granule, water extraction process, content determination, extract yield, orthogonal design

CLC Number: 

  • R284.2