Shandong Science ›› 2020, Vol. 33 ›› Issue (1): 42-50.doi: 10.3976/j.issn.1002-4026.2020.01.007
• Pharmacology and Toxicology • Previous Articles Next Articles
DU Hai-tao1,2, SUN Tie-feng2, WANG Ping2,3*, AN Feng-tian4, HU Ya-nan1, LI Na1
Received:2019-07-25
Published:2020-02-20
Online:2020-02-13
CLC Number:
DU Hai-tao, SUN Tie-feng, WANG Ping, AN Feng-tian, HU Ya-nan, LI Na. Advances in respiratory syncytial virus and its infection-related Toll-like receptors[J].Shandong Science, 2020, 33(1): 42-50.
| 1 |
YOU D H, SARAVIA J, SIEFKER D, et al. Crawling with virus:translational insights from a neonatal mouse model on the pathogenesis of respiratory syncytial virus in infants [J]. Journal of Virology, 2016, 90(1): 2-4.
doi: 10.1128/jvi.01026-15 |
| 2 |
SCHMIDT H, DAS A, NAM H, et al. Epidemiology and outcomes of hospitalized adults with respiratory syncytial virus: a 6-year retrospective study[J]. Influenza and Other Respiratory Viruses, 2019, 13(4): 331-338.
doi: 10.1111/irv.12643 |
| 3 |
NAIR H, NOKES D J, GESSNER B D, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis[J]. The Lancet, 2010, 375(9725): 1545-1555.
doi: 10.1016/S0140-6736(10)60206-1 |
| 4 |
CARIO E, PODOLSKY D K. Differential alteration in intestinal epithelial cell of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease[J]. Infection and Immunity, 2000, 68(12): 7010-7017.
doi: 10.1128/iai.68.12.7010-7017.2000 |
| 5 | 谢晓虹. 呼吸道合胞病毒感染后气道上皮细胞株Toll样受体表达及其功能研究[D]. 重庆: 重庆医科大学, 2009. |
| 6 |
刘娟娟, 张婷, 米芋枚. 呼吸道合胞病毒感染对气道上皮细胞表皮生长因子受体、紧密连接相关蛋白及黏蛋白表达的影响[J]. 中国当代儿科杂志, 2019, 21(3): 294-299.
doi: 10.7499/j.issn.1008-8830.2019.03.020 |
| 7 |
BAWAGE S S, TIWARI P M, PILLAI S, et al. Recent advances in diagnosis, prevention, and treatment of human respiratory syncytial virus[J]. Advances in Virology, 2013, 2013: 1-26.
doi: 10.1155/2013/595768 |
| 8 |
SUN Y, KIM EJ, FELT SA, et al. A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes[J]. PLoS Pathogens,2019,15(4): e1007707.
doi: 10.1371/journal.ppat.1007707 |
| 9 |
MASTRANGELO P, HEGELE R. RSV fusion: time for a new model[J]. Viruses, 2013, 5(3): 873-885.
doi: 10.3390/v5030873 |
| 10 |
BOYINGTON J C, JOYCE M G, SASTRYM, et al. Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus[J]. PLoS One, 2016, 11(7): e0159709.
doi: 10.1371/journal.pone.0159709 |
| 11 |
WIEGAND M A, GORI-SAVELLINI G, GANDOLFO C, et al. A respiratory syncytial virus vaccine vectored by a stable chimeric and replication-deficient Sendai virus protects mice without inducing enhanced disease [J]. Journal of Virology, 2017, 91(10): e02298.
doi: 10.1128/jvi.02298-16 |
| 12 |
RALLABHANDI P, PHILLIPS R L, BOUKHVALOVA M S, et al. Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2[J]. mBio, 2012, 3(4): e00218.
doi: 10.1128/mbio.00218-12 |
| 13 |
ARAUJO G C, SILVA R H T, SCOTT L P B, et al. Structure and functional dynamics characterization of the ion channel of the human respiratory syncytial virus (hRSV) small hydrophobic protein (SH) transmembrane domain by combining molecular dynamics with excited normal modes[J]. Journal of Molecular Modeling, 2016, 22(12): 286.
doi: 10.1007/s00894-016-3150-6 |
| 14 |
TAWAR R G, DUQUERROY S, VONRHEIN C, et al. Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus[J]. Science, 2009, 326(5957): 1279-1283.
doi: 10.1126/science.1177634 |
| 15 |
BARIK S. Respiratory syncytial virus mechanisms to interfere with type 1 interferons[M]//Current Topics in Microbiology and Immunology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013: 173-191.
doi: 10.1007/978-3-642-38919-1_9 |
| 16 |
LO M S, BRAZAS R M, HOLTZMAN M J. Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 and alpha/beta interferon responsiveness[J]. Journal of Virology, 2005, 79(14): 9315-9319.
doi: 10.1128/jvi.79.14.9315-9319.2005 |
| 17 |
BOSSERT B, MAROZIN S, CONZELMANN K K. Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3[J]. Journal of Virology, 2003, 77(16): 8661-8668.
doi: 10.1128/jvi.77.16.8661-8668.2003 |
| 18 |
汪旻旻, 孙涛, 袁晓玲, 等. NS2激活TLR7抑制RSV感染肺泡上皮细胞中IFN的表达[J]. 安徽医科大学学报, 2017, 52(11): 1632-1637.
doi: 10.19405/j.cnki.issn1000-1492.2017.11.011 |
| 19 |
SUN Y, L-PEZ C B. The innate immune response to RSV: advances in our understanding of critical viral and host factors[J]. Vaccine, 2017, 35(3): 481-488.
doi: 10.1016/j.vaccine.2016.09.030 |
| 20 |
dI GIOIA M, ZANONI I. Toll-like receptor co-receptors as regulators of the immune response[J]. Molecular Immunology, 2015, 63(2): 143-152.
doi: 10.1016/j.molimm.2014.05.008 |
| 21 |
CHAN Y K, GACK M U. Viral evasion of intracellular DNA and RNA sensing[J]. Nature Reviews Microbiology, 2016, 14(6): 360-373.
doi: 10.1038/nrmicro.2016.45 |
| 22 |
YONEYAMA M, ONOMOTO K, JOGI M, et al. Viral RNA detection by RIG-I-like receptors[J]. Current Opinion in Immunology, 2015, 32: 48-53.
doi: 10.1016/j.coi.2014.12.012 |
| 23 |
WANG S, ZHENG G, ZHAO L, et al. Shp-2 contributes to anti-RSV activity in human pulmonary alveolar epithelial cells by interfering with the IFN-α-induced Jak/Stat1 pathway[J]. Journal of Cellular and Molecular Medicine,2015,19(10):2432-40.
doi: 10.1111/jcmm.12629 |
| 24 |
SEGOVIA J, SABBAH A, MGBEMENA V, et al. TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection[J]. PLoS One, 2012, 7(1): e29695.
doi: 10.1371/journal.pone.0029695 |
| 25 |
MURAWSKI M R, BOWEN G N, CERNY A M, et al. Respiratory syncytial virus activates innate immunity through Toll-like receptor 2[J]. Journal of Virology, 2009,83(3):1492-1500.
doi: 10.1128/JVI.00671-08 |
| 26 |
YANG F, LI X, YANG Y, et al. A polysaccharide isolated from the fruits of Physalis alkekengi L. induces RAW264.7 macrophages activation via TLR2 and TLR4-mediated MAPK and NF-κB signaling pathways[J]. International Journal of Biological Macromolecules,2019,140:895-906.
doi: 10.1016/j.ijbiomac.2019.08.174 |
| 27 |
ASANKA SANJEEWA K K, JAYAWARDENA T U, Kim H S, et al. Fucoidan isolated from Padina commersonii inhibit LPS-induced inflammation in macrophages blocking TLR/NF-κB signal pathway[J]. Carbohydrate Polymers,2019,224:115195.
doi: 10.1016/j.carbpol.2019.115195 |
| 28 |
崔振泽,徐超,迟磊.基于“肺肠理论”和胆汁酸代谢网络探讨定喘汤对呼吸道合胞病毒感染大鼠肠道菌群调节的研究[J].中国中西医结合儿科学,2018,10(06):461-465.
doi: 10.13288/j.11-2166 /r.2019.11.007 |
| 29 |
CYR S L, ANGERS I, GUILLOT L, et al. TLR4 and MyD88 control protection and pulmonary granulocytic recruitment in a murine intranasal RSV immunization and challenge model[J]. Vaccine, 2009, 27(3): 421-430.
doi: 10.1016/j.vaccine.2008.10.073 |
| 30 | 李萌, 戴启刚, 汪受传, 等. 金欣口服液对呼吸道合包病毒感染RAW264.7细胞及BALB/c小鼠TLRs负性调控因子A20表达的影响[J]. 中华中医药杂志, 2014, 29(8): 2480-2483. |
| 31 | 黄艳娴. rhIFN-α1b对RSV感染鼠肺病变及JAK/STAT和TLR4/NF-κB信号通路的影响[D]. 西安: 第四军医大学, 2015. |
| 32 | 李涛. 金欣口服液对RSV活化诱导的TLR4信号转导通路的作用机制研究[D]. 南京: 南京中医药大学, 2014. |
| 33 |
YUAN X L, HU T, HE H W, et al. Respiratory syncytial virus prolifically infects N2a neuronal cells, leading to TLR4 and nucleolin protein modulations and RSV F protein co-localization with TLR4 and nucleolin[J]. Journal of Biomedical Science, 2018, 25: 13.
doi: 10.1186/s12929-018-0416-6 |
| 34 |
ZHU H, FU Z, GAO L, et al. Genetic polymorphisms of toll-like receptor 4 are associated with respiratory syncytial virus infection in a Chinese infant population[J]. Clinical Laboratory, 2015, 61(10): 1391-1399.
doi: 10.7754/clin.lab.2015.150145 |
| 35 |
汪茂荣, 朱进, 张怡青, 等. 抗人Toll样受体4单克隆抗体的制备及其生物活性研究[J]. 免疫学杂志, 2011, 27(7): 599-602.
doi: 10.13431/j.cnki.immunol.j.20110141 |
| 36 | 何汉文. TLR3、TLR7受体在呼吸道合胞病毒感染A549细胞诱导Ⅰ型干扰素中的作用研究[D]. 合肥: 安徽医科大学, 2015. |
| 37 |
SONG S, LEE J J, KIM H J, et al. Fas-associated factor 1 negatively regulates the antiviral immune response by inhibiting translocation of interferon regulatory factor 3 to the nucleus[J]. Molecular and Cellular Biology, 2016,36(7):1136-1151.
doi: 10.1128/MCB.00744-15 |
| 38 |
GUINN ZiP. Interferon regulatory factor 3 plays a role in macrophage responses to interferon-γ[J]. Immunobiology,2019,224:565-574.
doi: 10.1016/j.imbio.2019.04.004 |
| 39 |
WANG G, KOUWAKI T, MUGIKURA K,et al. Cytoplasmic dsRNA induces the of and mRNAs in differentiated human cells[EB/OL].[2019-05-12].http://dx.doi.org/10.1074/jbc.RA119.009783.
doi: 10.1074/jbc.RA119.009783 |
| 40 |
KO R,PARK H, LEE N,et al.Glycogen synthase kinase3 β regulates antiviral responses of TLR3 via TRAF2-Src Axis[J].J Immunol, 2019,203(11):2990-2999.
doi: 10.4049/jimmunol.1900685 |
| 41 |
LIM H K,HUANG S X L,CHEN J,et al.Severeinfluenza pneumonitis in children with inherited TLR3 deficiency[J].The Journal of Experimental Medicine,2019,216:2038-2056.
doi: 10.1084/jem.20181621 |
| 42 |
何汉文, 王葱, 杜博易, 等. TLR7在呼吸道合胞病毒感染A549细胞诱导Ⅰ型干扰素中的作用[J]. 安徽医科大学学报, 2015,50(11): 1560-1565.
doi: 10.19405/j.cnki.issn1000-1492.2015.11.007 |
| 43 |
HOSAKOTE Y M, JANTZI P D, ESHAM D L, et al. Viral-mediated inhibition of antioxidant enzymes contributes to the pathogenesis of severe respiratory syncytial virus bronchiolitis[J]. American Journal of Respiratory and Critical Care Medicine, 2011, 183(11): 1550-1560.
doi: 10.1164/rccm.201010-1755oc |
| 44 |
CASTRO S M, GUERRERO-PLATA A, SUAREZ-REAL G, et al. Antioxidant treatment ameliorates respiratory syncytial virus–induced disease and lung inflammation[J]. American Journal of Respiratory and Critical Care Medicine, 2006, 174(12): 1361-1369.
doi: 10.1164/rccm.200603-319oc |
| 45 |
朱童娜, 吴璇, 邱欢, 等. 呼吸道合胞病毒感染人肺上皮细胞诱导氧化应激对TLR7基因及其下游因子表达的影响[J]. 安徽医科大学学报, 2014,49(11): 1539-1543.
doi: 10.19405/j.cnki.issn1000-1492.2014.11.004 |
| 46 |
SUN T, YU H Y, ZHANG C L, et al. Respiratory syncytial virus infection up-regulates TLR7 by inducing oxidative stress via the Nrf2/ARE pathway in A549 cells[J]. Archives of Virology, 2018, 163(5): 1209-1217.
doi: 10.1007/s00705-018-3739-4 |
| 47 |
韩欢, 古今刚, 吴文文, 等. 11744例儿童7项呼吸道病毒抗原检测结果[J]. 武汉大学学报(医学版), 2019, 40(3): 425-428.
doi: 10.14188/j.1671-8852.2018.1276 |
| 48 |
杜海涛,孙铁锋,王平, 等. 清热药抗呼吸道合胞病毒的研究进展[J].中成药,2019,41(10):2435-2441.
doi: 10. 3969 /j.issn.1001-1528. 2019. 10. 031 |
| 49 |
黄燕, 徐超, 崔振泽, 等. 定喘汤对呼吸道合胞病毒感染大鼠体内免疫网络平衡因子的影响研究[J]. 中医儿科杂志, 2018, 14(2): 10-15.
doi: 10.16840/j.issn1673-4297.2018.02.03 |
| 50 |
覃黎葵, 张奉学, 黄笑娟, 等. 银翘散对呼吸道合胞病毒感染小鼠呼吸系统的作用研究[J]. 新中医, 2018, 50(5): 24-30.
doi: 10.13457/j.cnki.jncm.2018.05.006 |
| 51 |
徐建亚, 彭璐璐, 汪受传, 等. 金欣口服液对RSV感染细胞TLR4及TNF-α表达的影响[J]. 南京中医药大学学报, 2012, 28(6): 544-547.
doi: 10.14148/j.issn.1672-0482.2012.06.017 |
| 52 |
杜江. 金银花主要成分绿原酸对RSV感染RAW264.7细胞的TLR3信号通路的影响[J]. 齐齐哈尔医学院学报, 2017, 38(6): 626-628.
doi: 10.3969/j.issn.1002-1256.2017.06.003 |
| 53 |
云云, 汪长中, 桂丽, 等. 黄芩苷经由TLR4信号转导通路抗呼吸道合胞病毒作用的研究[J]. 中成药, 2013, 35(6): 1116-1121.
doi: 10.3969/j.issn.1001-1528.2013.06.002 |
| 54 | 谢秀春. 金欣口服液对干扰TLR4表达后RSV诱导的TRIF/NFκB调控作用[D]. 南京: 南京中医药大学, 2014. |
| 55 | 范奕熳, 袁斌, 周立华, 等. 清肺口服液对呼吸道合胞病毒感染小鼠IL-2和IL-10水平的影响[J]. 中华中医药杂志, 2017, 32(8): 3696-3699. |
|
||
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0), which permits third parties to freely share (i.e., copy and redistribute the material in any medium or format) and adapt (i.e., remix, transform, or build upon the material) the articles published in this journal, provided that appropriate credit is given, a link to the license is provided, and any changes made are indicated. The material may not be used for commercial purposes. For details of the CC BY-NC 4.0 license, please visit: https://creativecommons.org/licenses/by-nc/4.0