红果樫木叶木脂素类化学成分研究

doi:10.3976/j.issn.1002-4026.20230094

Abstract

Abstract:

To study the constituents of the leaves of Dysoxylum gotadhora, the 70% ethanol extract was separated using macroporous resin column chromatography, silica gel column chromatography, Sephadex LH-20 gel column chromatography, combined with semi-preparative HPLC and other methods. Four compounds 4,4'-dihydroxy-3,3',5,5'-trtramethoxy-7,9':7',9-diepoxylignane (1), 4'-hydroxy-3,4,5,3'-trtramethoxy-7,9':7',9-diepoxylignane (2), 4',4″-dihydroxy-3,3',3″,5,5',5″ -hexamethoxy-7,9':7',9-diepoxy-4,8″-oxy-8,8'-sesquineolignan-7″,9″-diol (3), 4',4″-dihydroxy-3,3',3″,5,5'-pentamethoxy-7,9':7',9-diepoxy-4,8″-oxy-8,8'-sesquineo lignan -7″,9″-diol (4) were isolated. Their structures were established by ¹H NMR, ¹³C NMR and MS spectroscopy techniques. Compounds 1 to 4 were obtained from the genus Dysoxylum for the first time. DPPH(1,1-diphenyl-2-picryhydrazyl radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl) radical scavenging rate were used to determine the antioxidant activity. The results show that lignans have significant DPPH free radical scavenging ability.

Key words: Dysoxylum gotadhora, chemical constituents, structure identification

CLC Number:

R284.1

YAN Huijiao, CHEN Yujie, SONG Xiangyun, LI Enxia, GENG Yanling. Lignan constituents from the leaves of Dysoxylum gotadhora[J].Shandong Science, 2024, 37(3): 10-17.

Figures/Tables 6

References 23

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Lignan constituents from the leaves of Dysoxylum gotadhora

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