Abstract:

Zebrafish models have been widely used in various fields such as drug screening, pharmacology, and toxicology research. In recent years, with the implementation of regulations such as the standard for the Evaluation of Cosmetic Efficacy Claims, cosmetic efficacy claims have entered into an era of strict supervision, which has led to higher standards for the scientific nature of the efficacy evaluation models and methods. The skin structure of zebrafish is highly similar to that of humans, with zebrafish also having transparent embryos that are easy to observe. Moreover, efficacy evaluation experiments using zebrafish offer advantages such as minimal sample dosage, shortened experimental cycles, and high-throughput capacity. Consequently, zebrafish have become a popular research topic in the field of cosmetic efficacy evaluation. Based on bibliometric methods, this study analyzes the relevant literature on the use of zebrafish to evaluate cosmetic efficacy over the past decade. The study provides an overview of the progress of the application of zebrafish in cosmetic efficacy evaluation, and examines the development dynamics and trends through comprehensive analysis. This is so as to provide a reference for the application of zebrafish models in the cosmetics industry.

Key words: zebrafish, cosmetics, efficacy evaluation