J4 ›› 2013, Vol. 26 ›› Issue (5): 10-13.doi: 10.3976/j.issn.1002-4026.2013.05.003

• Article • Previous Articles     Next Articles

Content determination of Sudan I with 1H NMR spectroscopy

 GENG Yan-Ling1, MA Ran2, LIU Wei1, GAO Hong-Mei1, LIU Jian-Hua1, WANG Xiao1, DUAN Wen-Juan1*   

  1. 1.Process Control Research Center of Traditional Chinese Medicine, Shandong Analysis and Test Center, Jinan 250014, China; 2. School of Life Sciences, Shandong Normal University, Jinan 250014, China
  • Received:2013-06-19 Published:2013-10-20 Online:2013-10-20

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Abstract:

We established a rapid and accurate method for the content determination of Sudan I with 1H NMR spectroscopy. We acquired 1H NMR spectra of the mixture of Sudan I and benzoic acid at 25 ℃ with Varian 600 MHz spectrometer, CDCl3 as solution, benzoic acid as internal standard. We determined the content of 99.47 %, 99.34 % and 99.51% of 3 batches of Sudan I. Results show that the method can be applied to content determination and quality control of Sudan I.

Key words: 1H NMR spectroscopy, content determination, Sundan I

CLC Number: 

  • O657.61

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