基于斑马鱼模型的昆海姜辛汤组分配伍的抗炎作用研究

doi:10.3976/j.issn.1002-4026.2017.02.006

Abstract

Abstract:

To study the anti-inflammatory effects of one marine medicine, compound Kunhai ginger decoction, whose component was prepared in different combination, zebrafish inflammatory model was established, induced by copper sulfate solution. The model was intervened by different concentrations of component combination solution from Kunhai ginger decoction (100, 50, 25 μg/mL) respectively, and its effect on the number of macrophage cell in zebrafish was observed by stereo fluorescence microscope. The results reveal that the number of macrophage cell in zebrafish inflammatory model induced by copper sulfate is reduced obviously due to the component combination solution from compound Kunhai ginger decoction, which has in vivo antiinflammatory effects.

Key words: component combination, anti-inflammatory, Kunhai ginger decoction, zebrafish

CLC Number:

R965.1

PENG Wei-bing, ZHOU Ling-xiao, FU Xian-jun, HE Qiu-xia, WANG Zhen-guo, LIU Ke-chun. Anti-inflammatory research on component combination of Kunhai ginger decoction based on zebrafish model[J].SHANDONG SCIENCE, 2017, 30(2): 37-42.

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Anti-inflammatory research on component combination of Kunhai ginger decoction based on zebrafish model

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