Shandong Science ›› 2020, Vol. 33 ›› Issue (3): 53-61.doi: 10.3976/j.issn.1002-4026.2020.03.008

• Traditional Chinese medicine and natural active products • Previous Articles     Next Articles

Investigation on preparation process of pigskin collagen peptide-zinc chelate

WU Jia-jin, BIAN Zhi-jie, ZHU Yue,ZHANG Xue-tao,PANG Li-dan, GAO Peng   

  1. School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
  • Online:2020-05-29 Published:2020-06-01

Abstract: This paper studies the preparation process of pigskin collagen peptide-zinc chelate. Pigskin was used as a raw material to prepare the pigskin collagen peptide-zinc chelate, and the effect of mass ratio of pigskin collagen peptide and zinc, pH, temperature, and time on the chelating rate, which was used as the index, was studied. We used a single-factor method and the response surface method to investigate zinc-rich technology of pigskin peptide. The results showed that the best technology for pigskin peptide-zinc chelation involved pigskin peptide-zinc mass ratio of 2:1 and a process with pH 7.0, 50 ℃, and 50 min for the chelation, resulting in the highest chelating rate of 69.27%, which was close to the predicted 69.92%. This study provides a basis for the development of new biological peptide-zinc chelation and the maximum utilization of pigskin.

Key words: pigskin collagen peptide, enzymatic hydrolysis, zinc, chelation process, response surface methodology

CLC Number: 

  • R284.2