Shandong Science

   

Optimization of rice-stirred ganoderma processing by AHP-EWM and response surface methodology and comparative study on antioxidant activity before and after processing

LI Zhiyong, LIU Jiangting, ZHANG Gouying, YANG Xueqi, ZHANG Mengxia,ZHAO Pan*, ZHANG Xiuyun*   

  1. College of Pharmacy, Shandong Uniersity of Traditional Chinese Medicine, Jinan 250355, China
  • Received:2025-01-08 Accepted:2025-03-05 Online:2026-03-24
  • Contact: ZHAO Pan, ZHANG Xiuyun E-mail:zhao.pan.pan@163.com;zhangxiuyunsh@163.com

Abstract: This study aimed to optimize the rice-fried processing technology of Ganoderma lucidum, determine the optimal processing parameters, and evaluate the impact of fried Ganoderma lucidum rice on its antioxidant activity.The processing temperature, processing time, and ratio of medicinal material to auxiliary materialwere used as the influencing factors, and the contents of Ganoderma lucidum polysaccharides, triterpenoids, and extracts, as well as the appearance score of the processed productwere used as evaluation indexes. The optimal rice-fried processing parameters were determined using the Analytic Hierarchy Process (AHP)-Entropy Weight Method combined with Box-Behnken Design and Response Surface Method.The antioxidant activity before and after processing was compared using ABTS?, DPPH, and hydroxyl radical scavenging assays. The optimized process conditions were as follows:processing temperature of 158.91°C, frying time of 10.18 minutes, and a material-to-auxiliary ratio of 1:0.20. The average comprehensive score obtained from process validation was 91.24 with a relative standard deviation of 0.81%. In vitro antioxidant activity assay results showed that the radical scavenging ability of Ganoderma lucidumsignificantly increased after processing (P < 0.01). The optimized rice-fr process is reliable, stable, and feasible. The rice-fried Ganoderma lucidum prepared using this process exhibited enhanced antioxidant activity, providing a reference for the processing technology and clinical application of Ganoderma lucidum.

Key words: rice-fired Ganoderma lucidum, Box-Behnken response surface method, analytic hierarchy process, entropy weight method, antioxidant activity

CLC Number: 

  • R283.3

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