Abstract: The agar plate-drilling method, Oxford cup method, and drug-sensitive tablet method were used to detect the in vitro bacteriostatic activities of ten Chinese herbal medicines, namely Paederia scandens, Lycii cortex, Pulsatillae radix, Isatidis folium, Taraxaci Herba, Schisandrae chinensis Fructus, Mume fructus, Folium artemisiae argyi, Coptidis rhizoma, and Salviae miltiorrhizae radix, on Salmonella pullorum. In addition, a single Chinese herbal medicine with better in vitro bacteriostatic effect was screened. The results showed that Schisandrae chinensis fructus and Mume fructus were highly sensitive to Salmonella pullorum, whereas Salviae miltiorrhizae radix and Coptidis rhizoma were generally sensitive to Salmonella pullorum. The other six Chinese herbal medicines were not sensitive to Salmonella pullorum. These results suggest that Schisandrae chinensis fructus and Mume frutus have certain antibacterial effects on Salmonella pullorum and that different Chinese herbal medicines have different antibacterial effects. This study provides a basis for the clinical treatment of Salmonella pullorum as well as for the development of Chinese herbal medicine preparations.

Key words: Salmonella pullorum, Chinese herbal medicine, in vitro bacteriostatic