铁离子引起的DNA电荷逆转和凝聚

doi:10.3976/j.issn.1002-4026.2016.04.018

山东科学 ›› 2016, Vol. 29 ›› Issue (4): 93-98.doi: 10.3976/j.issn.1002-4026.2016.04.018

铁离子引起的DNA电荷逆转和凝聚

郭子龙,王艳伟*,杨光参*

温州大学物理与电子信息工程学院，浙江温州 325035

收稿日期:2016-04-19 出版日期:2016-08-20 发布日期:2016-08-20
通信作者: 杨光参，Email:yanggc@wzu.edu.cn; 王艳伟，Email:wangyw@wzu.edu.cn E-mail:yanggc@wzu.edu.cn;wangyw@wzu.edu.cn
作者简介:郭子龙，男，硕士研究生，研究方向为生命现象中的凝聚态物理。
基金资助:
国家自然科学基金（11274245, 10974146, 11304232, 11444006）

Ferric ion induced DNA charge inversion and condensation

GUO Zi-long, WANG Yan-wei*, YANG Guang-can*

School of Physics and Electronic Information Engineering, Wenzhou University, Wenzhou 325035, China

Received:2016-04-19 Online:2016-08-20 Published:2016-08-20

摘要/Abstract

摘要：

在生物体中，DNA会凝聚成紧密结构，对于遗传信息的储存和转录有重要意义。对于DNA的凝聚以及伴随的电荷逆转已经有了比较深入的研究，这些研究大多集中于一些水解性较弱的离子，而对于那些易水解对于溶液pH影响较大的金属离子（例如铁离子）的研究较少。本文系统地研究了铁离子引起的DNA电荷逆转和凝聚，通过与DNA在三氯六氨络合钴凝聚的对比，探索了铁离子引起的DNA的电荷逆转和凝聚的可能机制。

关键词: DNA, 电荷逆转, 凝聚, 铁离子

Abstract:

The fact that DNA is condensed into a compact structure in an organism is very important for the storage and transcription of genetic information. Previous intensive studies involve DNA condensation and associated charge inversion. Most of them highlight polyamines and worse hydrolytical ions, but less of them involve easy hydrolytical and pH greatly influenced metallic ion (such as ferric ion). We systematically investigate ferric ion induced DNA charge inversion and condensation.By comparison with cobalt hexamine, we explore a possible mechanism of ferric ion induced DNA charge inversion and condensation.

Key words: charge inversion, ferric ion, DNA, condensation

中图分类号:

郭子龙,王艳伟,杨光参. 铁离子引起的DNA电荷逆转和凝聚[J]. 山东科学, 2016, 29(4): 93-98.

GUO Zi-long, WANG Yan-wei, YANG Guang-can. Ferric ion induced DNA charge inversion and condensation[J]. SHANDONG SCIENCE, 2016, 29(4): 93-98.

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铁离子引起的DNA电荷逆转和凝聚

Ferric ion induced DNA charge inversion and condensation

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