J4 ›› 2014, Vol. 27 ›› Issue (2): 39-43.doi: 10.3976/j.issn.1002-4026.2014.02.008

• 中药与天然活性产物专栏 • 上一篇    下一篇

性状异常丹参的利用价值研究

李翠1,2,尉广飞1,李佳1,郑立谋2,张永清1   

  1. 1.山东中医药大学,山东 济南 250355; 2.河南省灵宝市阳店镇农业服务中心,河南 三门峡 472500
  • 收稿日期:2013-12-12 出版日期:2014-04-20 发布日期:2014-04-20
  • 通信作者: 张永清(1962-),男,理学博士,教授,博士生导师,研究方向为中药资源及其质量控制。 E-mail:zyq622003@126.com
  • 作者简介:李翠(1982-),女,博士研究生,研究方向为中药资源及其质量控制研究。

Research on the utilization value of Salvia miltiorrhiza with abnormal characters

LI Cui1,2, WEI Guang-Fei1, LI Jia1, ZHENG Li-Mou2, ZHANG Yong-Qing1   

  1. 1.Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 2.Yangdian Town Agricultural Service Center, Sanmenxia 472500, China
  • Received:2013-12-12 Online:2014-04-20 Published:2014-04-20

摘要:

本文研究性状异常丹参是否具有利用价值。采用HPLC法,Diamonsil C18色谱柱(4.6 mm×250 mm,5 μm),乙腈0.026 %磷酸溶液梯度洗脱,检测波长为270、286 nm,流速为1.0 mL·min-1,测定各样品中活性成分含量。结果表明,患病、变色等性状异常的丹参仍含有迷迭香酸、丹酚酸B、丹参酮ⅡA、丹参酮Ⅰ及隐丹参酮等活性成分,部分活性成分含量甚至比正常丹参高数倍,可以作为工业化提取迷迭香酸、丹参酮ⅡA、丹酚酸B等的原材料。

关键词: 性状异常, 丹参, 高效液相色谱法, 价值研究

Abstract:

This paper addressed whether Salvia miltiorrhiza with abnormal characters had utilization value. The content of its effective components was measured by HPLC under the conditions of Diamonsil C18 column (4.6 mm×250 mm,5 μm), acetonitrile0.026% phosphoric acid gradient elution, detection wave length of 270 nm and 286 nm and flow rate of 1.0mL·min-1. Results show that Salvia miltiorrhiza with such abnormal characters as sicks and discolour still contains such active ingredients as rosmarinic acid, salvianolic acid B, tanshinone Ⅱ A, tanshinone I and cryptotanshinone. The contents of cryptotanshinone and tanshinone I in abnormal Salvia miltiorrhiza are several times than those in normal Salvia miltiorrhiza. Abnormal Salvia miltiorrhiza can therefore serve as Chinese medicine raw material with which Rosmarinic acid and Salvianolic acid B can be extracted.

Key words: abnormal character, Salvia miltiorrhiza, HPLC, value research

中图分类号: 

  • R284.1