模式生物斑马鱼在听觉领域的应用

doi:10.3976/j.issn.1002-4026.2019.05.005

摘要/Abstract

摘要： 耳聋疾病严重影响着患者的生存质量。选择合适的模式生物，对耳聋疾病进行研究，可为该疾病的治疗和药物研发等提供可靠数据。斑马鱼是近年来兴起研究的一种新型脊椎动物模式生物，具有独特的自身优势，其在听觉领域的应用正日益受到人们的关注。基于此，就斑马鱼在听觉领域的研究优势、应用进展以及常用的技术方法等进行了综述。

关键词: 斑马鱼, 听觉系统, 研究优势, 应用进展, 技术方法

Abstract: Hearing loss has a substantial effect on the quality of patients′ life. The study on hearing loss using appropriate model organisms can provide reliable data for disease treatment and drug development. Zebrafish has emerged as a new type of vertebrate model organism in recent years. Because of its unique advantages, there is a growing interest in the use of zebrafish in research related to human hearing disorders. Considering this scenario, the paper reviews the research advantages, application progress, and common techniques used in the field of hearing research involving zebrafish.

Key words: zebrafish, auditory system, research advantage, application progress, technique

中图分类号:

R319

刘可春, 高燕, 张云, 何秋霞, 韩利文, 李宁, 季秀娜, 孙晨. 模式生物斑马鱼在听觉领域的应用[J]. 山东科学, 2019, 32(5): 46-53.

LIU Ke-chun, GAO Yan, ZHANG Yun, HE Qiu-xia, HAN Li-wen, LI Ning, JI Xiu-na, SUN Chen. Zebrafish as a model organism for hearing research[J]. Shandong Science, 2019, 32(5): 46-53.

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