山东科学 ›› 2017, Vol. 30 ›› Issue (5): 14-20.doi: 10.3976/j.issn.1002-4026.2017.05.003

• 中药与天然活性产物 • 上一篇    下一篇

微波消解 ICP-MS法测定青海和西藏产区冬虫夏草中的35种元素

张敏敏1,赵恒强1,赵志国1,刘伟1,刘倩1,梁琰1,耿岩玲1,黄璐琦2,王晓1*   

  1. 1. 山东省中药质量控制技术重点实验室,山东省科学院中药过程控制研究中心,山东省分析测试中心,山东 济南 250014;2. 中国中医科学院中药资源中心,
    道地药材国家重点实验室培育基地,中国中医科学院,北京 100700
  • 收稿日期:2017-05-10 出版日期:2017-10-20 发布日期:2017-10-20
  • 通信作者: 王晓(1971—),男,研究员,博士,研究方向为中药质量控制研究。Tel: 0531-82605319,E-mail: wxjn1998@126.com E-mail:wxjn1998@126.com
  • 作者简介:张敏敏(1990—),女,硕士研究生, 研究方向为中药分析与质量控制。E-mail:zhangminminff@163.com
  • 基金资助:

    中央本级重大增减支项目(2060302);国家自然科学基金重点项目(81130070)

Determination of 35 elements in Chinese caterpillar fungus from Qinghai and Tibet by microwave digestionICP-MS

ZHANG Min-min1,ZHAO Heng-qiang1,ZHAO Zhi-guo1,LIU Wei1,LIU Qian1,LIANG Yan1,GENG Yan-ling1,HUANG Lu-qi2,WANG Xiao1*   

  1. 1.Shandong Provincial Key Laboratory Breeding Base of TCM Quality Control Technology, Process Control Research Center of Traditional Chinese Medicine of Shandong Academy of Sciences, Shandong Analysis and Test Center,  Jinan 250014, China; 2.National Resource Chinese Center for Materia Medica, Key Laboratory of Road to  the Cultivation of Chinese Medicine ,China Academy of Chinese Medical Sciences, Beijing 100700,China
  • Received:2017-05-10 Online:2017-10-20 Published:2017-10-20

摘要:

为了测定青海和西藏产区的17批冬虫夏草中的35种元素(其中16种为稀土元素)的含量,并进行初步产地鉴别分析,运用微波消解ICPMS法测定了3批玉树、4批那曲和10批果洛产区的虫草样本,并对3个产区的测定结果进行聚类分析。结果表明,不同产区的虫草药材各种元素含量差别较大,本文对其中4种有害元素Cd, Pb, As, Cu推荐了限量标准;聚类分析结果表明,玉树和果洛产区聚类较近、差异性较小;那曲产区聚类较远,相对差异性较大。该方法快捷、准确、可行性强,为不同产地冬虫夏草药材的质控和用药安全指导提供了理论依据。

关键词: 冬虫夏草, 微量元素, 稀土元素, ICP-MS

Abstract:

To determine the contents of 35 elements (including 16 rare earth elements) in 17 batches of Chinese caterpillar fungus from Qinghai and Tibet and make preliminary identification analysis of their habitats, a total of 35 elements in Chinese caterpillar fungus samples were determined by microwave digestionICPMS, including 3 batches from Yushu, 4 batches from Naqu and 10 batches from Guoluo. Furthermore, cluster analysis was carried out on the measurement results of 3 producing areas. Results showed that the contents of 35 elements in 17 kinds of Chinese caterpillar fungus samples from different origins have obvious differences. And the limits of the 4 kinds of harmful elements (Cd, Pb, As and Cu) were recommended. The results of cluster analysis showed that the samples from Yushu and Guoluo were close, and the difference was small, while the sample from Naqu was far away, and its relative difference was larger. This method is quick, accurate and feasible, which provides a theoretical basis for quality control and medication guidance of Chinese caterpillar fungus from different habitats.

Key words: ICP-MS, rare earth elements, Chinese caterpillar fungus, trace elements

中图分类号: 

  • R284.1