山东科学 ›› 2021, Vol. 34 ›› Issue (2): 18-23.doi: 10.3976/j.issn.1002-4026.2021.02.003

• 中药与天然活性产物 • 上一篇    下一篇

十种中草药对雏沙门氏菌的体外抑菌试验

杨金波12,于忠娜1,李莉1,王钊1,于雷1*   

  1. 1.青岛农业大学海都学院,山东 莱阳 2652002.河北工程大学 生命科学与食品工程学院,河北 邯郸 056021
  • 收稿日期:2020-06-10 出版日期:2021-04-13 发布日期:2021-04-13
  • 通信作者: 于雷,女,讲师。E-mail:755970166@qq.com
  • 作者简介:杨金波(1998—),女,研究方向为动物医学。E-mail:2449499414@qq.com
  • 基金资助:
    青岛农业大学海都学院教学研究课题(JY201919

In vitro bacteriostatic test of ten Chinese herbal medicines against Salmonella pullorum

YANG Jin-bo1,2YU Zhong-na1,LI Li1,WANG Zhao1,YU Lei1*   

  1. 1.Haidu College·Qingdao Agricultural University, Laiyang 265200,China;2.College of Life Science and Food Engineering,Hebei University of Engineering,Handan 056021,China
  • Received:2020-06-10 Online:2021-04-13 Published:2021-04-13

摘要: 采用琼脂平板打孔法、牛津杯法和药敏片法,检测鸡矢藤、地骨皮、白头翁、大青叶、蒲公英、五味子、乌梅、艾叶、黄连、丹参10种中草药对雏沙门氏菌的体外抑菌效果,并从中筛选具有较好体外抑菌作用的单味中草药。结果表明,五味子和乌梅对雏沙门氏菌的抑菌效果敏感性较强,丹参和黄连的敏感性一般,其他6种中草药均不敏感。试验结果表明,五味子和乌梅等对雏沙门氏菌具有一定的抗菌作用,且不同的中草药抑菌效果不同。该研究为临床治疗鸡白痢以及开发中草药制剂提供了依据。

关键词: 雏沙门氏菌, 中草药, 体外抑制

Abstract: The agar plate-drilling method, Oxford cup method, and drug-sensitive tablet method were used to detect the in vitro bacteriostatic activities of ten Chinese herbal medicines, namely Paederia scandens, Lycii cortex, Pulsatillae radix, Isatidis folium, Taraxaci Herba, Schisandrae chinensis Fructus, Mume fructus, Folium artemisiae argyi, Coptidis rhizoma, and Salviae miltiorrhizae radix, on Salmonella pullorum. In addition, a single Chinese herbal medicine with better in vitro bacteriostatic effect was screened. The results showed that Schisandrae chinensis fructus and Mume fructus were highly sensitive to Salmonella pullorum, whereas Salviae miltiorrhizae radix and Coptidis rhizoma were generally sensitive to Salmonella pullorum. The other six Chinese herbal medicines were not sensitive to Salmonella pullorum. These results suggest that Schisandrae chinensis fructus and Mume frutus have certain antibacterial effects on Salmonella pullorum and that different Chinese herbal medicines have different antibacterial effects. This study provides a basis for the clinical treatment of Salmonella pullorum as well as for the development of Chinese herbal medicine preparations.

Key words: Salmonella pullorum, Chinese herbal medicine, in vitro bacteriostatic

中图分类号: 

  • S853.72