基于网络药理学和分子对接探讨猫爪草治疗肺腺癌的作用机制

刘幸, 黄红丽, 张乐, 刘向芳, 张文林, 沈凌筠

To explore the mechanism of Ranunculi Ternati Radix in the treatment of lung adenocarcinoma based on network pharmacology and molecular docking

LIU Xing, HUANG Hong-li, ZHANG Le, LIU Xiang-fang, ZHANG Wen-lin, SHEN Ling-jun

表1 猫爪草活性成分

Table 1 Active ingredients of Ranunculi Ternati Radix

编号 活性成分 OB/% DL MOL000242 7-O-Methyleridictyol(7-O-甲基圣草酚) 56.56 0.27 MOL011330 vittadinoside_qt(维太菊苷) 43.83 0.76 MOL000449 Stigmasterol(豆甾醇) 43.83 0.76 MOL006772 poriferasterol monoglucoside_qt(豆甾醇葡萄糖苷) 43.83 0.76 MOL011319 Truflex OBP(邻苯二甲酸正丁异辛酯) 43.74 0.24 MOL001494 Mandenol(亚油酸乙酯) 42.00 0.19 MOL001973 Sitosteryl acetate(谷甾醇乙酸酯) 40.39 0.85 MOL000593 CLR(胆固醇) 37.87 0.68 MOL005438 cmpesterol(菜油甾醇) 37.58 0.71 MOL000358 bate-sitosterol(β-谷甾醇) 36.91 0.75